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Trofile™ Info for Patients

Trofile™ is used to identify HIV tropism

Your doctor needs to know your HIV tropism before prescribing co-receptor antagonists. Your HIV has its own unique identity. Tropism refers to the co-receptor that a particular HIV strain uses to enter the CD4+ cell. The two most common co-receptors are CCR5 (R5) and CXCR4 (X4). Trofile™ is a novel test that pinpoints your tropism status –R5, X4, or a combination of these known as dual/mixed. Trofile reveals if your virus primarily uses the CCR5 co-receptor. This can help your doctor decide to prescribe a CCR5 antagonist. This new class of antiretrovirals targets CCR5-specific HIV entry into the cell.

What does tropism mean?

Tropism is the co-receptor HIV uses to get into your cells

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How does tropism affect my treatment plan?

If your HIV tropism is CCR5, there’s a new kind of medicine that can help stop HIV from getting in

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Why do I need a Trofile™ test?

  • Trofile™ is a test that identifies HIV tropism
  • Knowing your tropism can help your doctor find the right medicine for you
  • If your tropism type is R5, you are a candidate for maraviroc
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Knowing your tropism can help your doctor find the right medicine for you. We have provided a simple guide to help patients and non-medical professionals understand tropism and how it affects your HIV treatment plan.

Click to download Understanding Tropism


Helping guide individual HIV therapy Identifying alternative treatment options even when your HAART regimen is failing.

Click to download Helping guide individual HIV therapy